Based on the good writing about the goal of Fedora.next by Adam Williamson, Design Suite may be made on top of Fedora Workstation as the logical choice. Doing so will help focusing on key areas like configurations and proper distribution of applications to display better technologies (For example, Design Suite is using AppFolder provided by Gnome Shell as default). Fedora Workstation is a base with the ability to add group package like Design Packages in this case. Only difference with the spin is the optimization while staying close to upstream.
Busy weekend. I just took a break for making a presentation of Fedora Core 6 and Fedora Project for Vancouver Linux Users Group which will debut on November 20, 2006. A local computer store was kind enough to give me a laptop for the demonstration of Fedora Core 6 (Zod) live spin and Sugar interface from OLPC Project. Should you be interested to view that event and live near Vancouver, here is the address .